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Matthias Hammerschmidt Selected Research

cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)

2/2018Biallelic CHP1 mutation causes human autosomal recessive ataxia by impairing NHE1 function.
1/2018CHP1 reduction ameliorates spinal muscular atrophy pathology by restoring calcineurin activity and endocytosis.

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Matthias Hammerschmidt Research Topics

Disease

6Neoplasms (Cancer)
01/2020 - 02/2004
4Inflammation (Inflammations)
11/2021 - 07/2009
4Wounds and Injuries (Trauma)
01/2018 - 07/2012
3Spinal Muscular Atrophy (Progressive Muscular Atrophy)
01/2018 - 04/2014
3Craniosynostoses (Craniosynostosis)
04/2016 - 11/2011
2Psoriasis (Pustulosis Palmaris et Plantaris)
11/2021 - 08/2009
2Carcinoma (Carcinomatosis)
01/2020 - 09/2004
2Deafness (Deaf Mutism)
02/2018 - 12/2010
2Hearing Loss (Hearing Impairment)
11/2012 - 02/2011
2Fraser Syndrome
09/2012 - 04/2010
1Obesity
01/2022
1Carcinogenesis
01/2020
1Ataxia (Dyssynergia)
02/2018
1Cakut
01/2018
1Edema (Dropsy)
01/2016
1Gastrointestinal Stromal Tumors (Gastrointestinal Stromal Tumor)
09/2015
1Body Weight (Weight, Body)
01/2015
1Hyperphagia (Overeating)
01/2015
1Infarction (Infarctions)
09/2014
1Neurodegenerative Diseases (Neurodegenerative Disease)
04/2014
1Conductive Hearing Loss
11/2013
1Exophthalmos (Proptosis)
11/2013
1Prognathism
11/2013
1Synostosis
11/2013
1Osteoporosis
10/2013
1Osteoporotic Fractures
10/2013
1Nonsyndromic Deafness
11/2012
1Tissue Adhesions
09/2012
1Autosomal Recessive 42 Deafness
02/2011
1Brachydactyly
12/2010
1Temtamy preaxial brachydactyly syndrome
12/2010
1Syndactyly (Polysyndactyly)
04/2010
1Blister (Bulla)
04/2010
1Type I Syndactyly
05/2008
1Pathologic Processes
03/2006

Drug/Important Bio-Agent (IBA)

10Proteins (Proteins, Gene)FDA Link
02/2018 - 07/2009
4EnzymesIBA
11/2021 - 02/2004
2cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)- somatostatin (CHP1)IBA
02/2018 - 01/2018
2Retinoic Acid 4-Hydroxylase (CYP26B1)IBA
04/2016 - 11/2011
2Tretinoin (Retinoic Acid)FDA LinkGeneric
04/2016 - 11/2011
2Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
12/2010 - 03/2006
1Glucose (Dextrose)FDA LinkGeneric
01/2022
1NADPH Oxidases (NAD(P)H oxidase)IBA
11/2021
1Nicotinamide PhosphoribosyltransferaseIBA
11/2021
1NAD (NADH)IBA
11/2021
1matriptaseIBA
01/2020
1Serine Proteases (Serine Protease)IBA
01/2020
1CalcineurinIBA
01/2018
1rho-Associated KinasesIBA
01/2018
1Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA
10/2017
1NeurocalcinIBA
01/2017
1Adenosine Triphosphatases (ATPase)IBA
01/2016
1IntegrinsIBA
01/2016
1Apoptosomes (Apoptosome)IBA
09/2015
1Small Interfering RNA (siRNA)IBA
09/2014
1UbiquitinIBA
04/2014
1CateninsIBA
04/2014
1Interleukin Receptors (Interleukin Receptor)IBA
11/2013
1Actins (F Actin)IBA
10/2013
1plastinIBA
10/2013
1Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
06/2013
1FibrinIBA
06/2013
1CollagenIBA
06/2013
1ribonuclease PH (RNase PH)IBA
11/2012
1Mitochondrial RNAIBA
11/2012
1fibulinIBA
09/2012
1Protein Isoforms (Isoforms)IBA
09/2012
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2012
1Cytochrome P450 Family 26IBA
11/2011
1Nonsense Codon (Nonsense Mutation)IBA
02/2011
1Initiator Codon (Start Codon)IBA
02/2011
1chondroitin synthaseIBA
12/2010
1FurinIBA
04/2010
1Interleukin-1beta (Interleukin 1 beta)IBA
08/2009
1Epithelial Cell Adhesion MoleculeIBA
07/2009
1Peptides (Polypeptides)IBA
07/2009
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2009
1beta CateninIBA
09/2004
1Polysaccharides (Glycans)IBA
02/2004
1Hyaluronic Acid (Hyaluronan)IBA
02/2004

Therapy/Procedure

2Caloric Restriction
01/2022 - 01/2015
2Sutures (Suture)
04/2016 - 11/2013
1Aftercare (After-Treatment)
01/2016
1Therapeutics
09/2015
1Surgical Instruments (Clip)
05/2008